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Clinical Investigation (MHS-CI) Track

The Clinical Investigation MHS Track aims to train the next generation of multidisciplinary clinicians, physician-scientists, and scientists in clinical investigation. Participants will learn to conduct rigorous clinical research, evaluate evidence-based practices, translate and reverse-translate findings to bring solutions to diseases, provide optimal care for patients, and enhance collaboration between scientists and clinicians.

Program Objectives

Expected skills upon program completion include:

  • Construct focused research questions and formulate testable hypotheses
  • Formulate and implement well-designed clinical and translational research studies
  • Critically evaluate strengths and weaknesses of clinical and translational research design
  • Effectively write scientific papers and evaluate scientific literature
  • Analyze experimental and observational designs
  • Grant writing
  • Teaching and mentoring

Course & Graduation Requirements

Participants must complete 32 credits, with four required courses and two elective courses. There is also a leadership development course shared across tracks.

To graduate, participants also must write and defend a thesis. The formal thesis can be waived if the student submits one first-author thesis project publication by graduation.

Sample Outline of Required Coursework:
MHS-Clinical Investigation
Year 1
Summer
Year 1
Fall
Year 1
Spring
Year 2
Summer
Year 2
Fall
Year 2
Spring
Molecular Genomic Pathology in Precision Medicine


X



Pragmatic Trial Design and Implementation




X

MHS Research in Progress Series

X
X

X
X
Mentored Thesis Research Project X
X
X
X
X
X
Elective: ie., Foundations of Epidemiology & Public Health Epidemiology


X



Elective: ie., Artificial Intelligence and Big Data





X
IMED630: Ethical Issues in Biomedical Research

X




IMED655: Writing your Career Development (K or R) Award





X
IMED645: Introduction to Biostatistics in Clinical Investigation
X





Time Allowance & Department Commitment

This is a two-year program requiring a 50-75% time commitment, which must be approved by your department chair or division chief in writing. This program is intended for those who plan to pursue a career at Yale. While this is not a strict requirement, because of Yale’s investment in the participant, it will be an important consideration. If a participant is unable to complete the degree in two years, approval of an extension is required by the Yale MHS Degree Program and the Track Academic Director.

Contact Us & Track Leadership

Clinical Investigation (MHS-CI) Track

  • Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology; Deputy Director, Yale Cancer Center; Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital; Assistant Dean for Translational Research, Yale School of Medicine; Director, Center for Thoracic Cancers, Yale Cancer Center and Smilow Cancer Hospital; Program Director, Master of Health Science - Clinical Investigation Track (MHS-CI)

How to Apply

Collect your letters of support, your personal statement, the description of your proposed research, and submit your application via the application form.